Heparin affinity resin

Heparin affinity chromatography resin can be applied for separation and purification of protein molecules that have specific binding with heparin molecules, including coagulation factors, antithrombin III, growth factors, interferon and lipase.

Heparin affinity chromatography resin uses super-macro-porous polyacrylate hard gel as matrix and adopts unique chemical bonding technology from Bogen (A Duoning company) to immobilize heparin molecules, separating protein of interest through the specific binding between heparin and antithrombin III or protein molecules with similar structures.

Product Features:

Ÿ   High protein-binding affinity

Ÿ   High protein recovery

Ÿ   Large pore size with low mass transfer resistance, suitable for purification of high viscosity samples

Case Study

Purification of antithrombin III

Column size: 1.0cm ID x 2.5cm，CV=2mL

Flow rate: 1mL/min

Sample: Pretreated genetically modified goat milk (after 0.45 μm membrane filter)

1.Elution peak P1 of Bogen resin

2.Elution peak P2 of Bogen resin

3.Elution peak P1 of competitor's resin

4.Elution peak P2 of competitor's resin

GP Series

Agarose series

Prepacked Heparin affinity chromatography column